WASEDA'S REGIMEN
AMASHISO + ANALYSIS ON HAIR LOSS

 

WASEDA'S COMPREHENSIVE ANALYSIS ON HAIR LOSS 
&
INTRODUCTION TO AMASHISO
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the following is reprinted from a series of posts submitted by Waseda in forum # 22.

Footnote # 9

(9) Androgen-inducible TGF-beta1 Derived from Dermal Papilla Cells Mediates Hair Growth Suppression in Androgenetic

Alopecia. Shigeki Inui, Yoko Fukuzato, Takeshi Nakajima, Kunihiko Yoshikawa, Satoshi Itami Department of Dermatology,

Osaka University Medical School(http://www.ehrs.org/conferenceabstracts/2001tokyo
/researchabstracts/008-inui.htm)

We further examined the change of expression level of mRNA of various factors in bald DPCs cocultured with keratinocytes after androgen treatment by semiquantitative RT-PCR and found that TGF-beta1 was increased by androgen in bald DPCs.

Moreover, the neutralizing anti-TGF-beta1 antibody antagonized the inhibition of keratinocyte proliferation in this co-culture system in a dose dependent manner. From these data obtained using our novel powerful coculture model for AGA, we suggest that androgen-inducible TGF-beta1 derived from DPCs mediates hair growth suppression in AGA.

 
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Footnotes to Waseda's Analysis


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Footnote 8
 
Footnote 9
 
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Footnote 13

 



                 

 

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