#5 HairSite: Can you tell us more about this technique that ARI is currently researching? Does it create a brand new follicle or does it rejuvenate existing dormant or inactive follicles?

Dr. Washenik: Our plan is to create new follicles. We don’t expect to rejuvenate dormant hair follicles, but if that happens, we would be thrilled and that would certainly be a very pleasant surprise.

This may sound like a marketing slogan, but Dr. Lee Bosley often says "hair transplantation is minor surgery but major artistry" because the doctor is deciding where to place the grafts in order to achieve the desired artistic effects. With tissue engineered hair growth or follicle neogenesis, we are creating a brand new follicle and the onus is on the person implanting the hair seeds to create an artistically acceptable result. On the contrary, if old follicles can be rejuvenated, that would be wonderful because we do not have to worry about the hair direction and angle. Everything is already predetermined by nature and we simply have to restart the process. Right now our focus is creation of new follicles, but I would be thrilled if we can rejuvenate dormant hair follicles too.

#6 HairSite: Since we are creating new follicles with this technique, does it mean that theoretically we can have more density than we were ever born?

Dr. Washenik: Yes.

#7 HairSite: Can you tell us more about the focus of this new technique? Is it just a basic form of cell therapy procedure or is it a more sophisticated technique that relies primarily on tissue engineering?

Dr. Washenik: We have one goal, i.e. the creation of new hair follicles. But to get there, we are not pursuing just one line of research. I find that research sometimes pulls you rather than you pushing the research. Very often you just follow the opportunities presented to you as you go along and you have to be prompt to react to any leads that are promising. Our one singular focus is to take cells from hair follicles, culture them, allow them to multiply and then repackage them in such a way that they can induce or create a new follicle when placed back into the scalp.

We are not working on two separate protocols. We use a combination of cell therapy and tissue engineering. Cell therapy research in Philadelphia, and tissue engineering research in Atlanta.

#8 HairSite: How would you compare Aderans’ research with other organizations or scientists who are also experimenting with a similar procedure for hair loss?

Dr. Washenik: Right now most researchers seem to pursue one basic concept. The focus is to take cells from hair follicles, culture them, allow them to multiply and then repackage them in such a way that they can induce or create a new follicle when placed back into the scalp. There are only two groups of cells to work with, follicular fibroblasts and follicular keratinocytes. Based on the scientific literature, researcher seems to suggest that the follicular fibroblast is the driving force in the formation of hair follicles. The different groups are bound to have some secrets or proprietary knowledge that are not shared with the public. It would be impossible for me to do a meaningful comparison just based on superficial observations.

What may be infuriating to you is that the thing that sets us apart from other researchers is the actual thing that I cannot discuss. The basic concept is public knowledge to everyone, but we are all doing something different.

#9 HairSite: Do you anticipate a nasty courtroom battle over the patent issues?

Dr. Washenik: People often say a patent is only an invitation to the courtroom. There will be arguments no matter who comes out with hair multiplication first. But I think it will eventually take care of itself. Right now I am not aware of anyone slowing down his research because of the anticipation of a courtroom battle. Also, the court may view the existing patents as so similar and so general that they will not be useful. If existing patents worked, we would have had hair multiplication available many years ago already. There are bound to be some secrets that maintain the inductive potential of the cells. I don’t envision the possibility of a nasty courtroom battle among the different groups. I envision there will be different versions of HM. There might be arguments, but I don’t think it will keep the technology from coming out to patients.

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