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SYNTHETIC
PEPTIDE FOR BALDNESS
HOLDS PROMISE October
1, 2002
Early
clinical trials of a synthetic peptide are showing promise in
re growing hair in alopecia patients, a condition that affects 50
million men and 30 million women in America.
WSMR's investigators
have designed a synthetic peptide that activates an obscure receptor
that sits on the surface of a patient's own hair
follicle cells. This peptide was then used to activate
the patient's hair follicles into growth phase.
The
study demonstrates that it is possible to get the human hair
follicle to recognize a synthetic peptide and the message from that
peptide. The synthetic peptide sequence is called Flexible
Peptide S (FLEX S) and is named due to its flexible binding
characteristics on the hair follicle cells.
There
are currently two separate sequences of FLEX S,
both of which switch the hair follicle into growth phase.
"It
now appears that we can restore all of the follicles on the scalp to
a healthy condition, the implications are profound" said
Slobodan Jankovic, M.D., Ph.D., Director of the Centre for Clinical
and Experimental Pharmacology, Dean of Medical Faculty,
University of Kragujevac Yugoslavia
.
Jankovic
went on to say "This indicates that even in slick balding areas
of the scalp the follicles are just miniaturized and can be switched
back on with the right synthetic peptide messenger."
Please
also click here to read Dr. Jankovic's letter to HairSite in
November 2003.
All of
the patients received a topical mixture containing the designer
peptide (FLEX S) and a special liposome like adjuvant
to enhance its uptake by the hair follicle.
"Safety
isn't a problem, because the peptide is too large to get from
the scalp into systemic circulation. It is almost like nature
intended this peptide to induce hair re-growth and not get to
the rest of the body." Said S.L (Bob) Hsia,
Ph.D. Professor of Dermatology & Cutaneous Surgery,
liposome and skin biology expert from the University of Miami School
of Medicine.
Dr.
Hsia who also is a scientific advisor to WSMR, went on to say
"The special design of the topical vehicle to take the
FLEX S peptide to the hair follicle is key to the
effectiveness."
"This
synthetic peptide is amazing, it acts just like a "hair
switch" turning on the follicles and making them begin growing
hair again." Commented John Emerson, M.D. a practicing
plastic surgeon and member of the SAB of WSMR.
But
Darren Green, Press consultant for WSMR Cautioned, "Yes, it
does appear that we have found a safe and completely effective
treatment for hair loss, but constructing complex synthetic peptides
like FLEX S 1 & 2 is currently very expensive. The product
could not become commercially available until the cost can be
reduced from the current level of almost $500 per month."
For
more information about FLEX S and other synthetic peptides that
induce hair growth visit WSMR's Website for patients, public and the
mass media at http://www.hairswitch.com
.
All
WSMR Related Stories:
WSMR
Press Release - Synthetic Peptide
WSMR Frequently Asked Questions + Safety Profile
WSMR Flexible Peptide S patient results
WSMR received seal of approval from JTR
WSMR test patient request form
Dr. Kenneth Skinner of WSMR speaks about HairSwitch
Interim update from WSMR HairSwitch peptide trialist.
HairSite spoke to WSMR's HairSwitch peptide trialists.
March 1, 2003: first official update from HairSwitch peptide
trialists.
November 2003: before and after photos.
Dr. Jankovic's comments about WSMR.
Alert: Please
be advised that HairSite is NOT recommending WSMR products to any of
our readers. Please exercised caution if you are considering
purchasing WSMR products as we are unable to verify if the product
is indeed effective for hair growth or otherwise. Also, while there
is no incriminating evidence which suggests that WSMR is a scam, we
believe that our readers should familiarize themselves with the
latest report by Rock Mountain News about WSMR. Click
here for JTR's post.
TOPICAL
FORUM
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