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WSMR'S
FLEXIBLE PEPTIDE S
FAQ & SAFETY PROFILE
What is FLEX S1, 2?
Flexible Peptide S or FLEX S1, 2 are two versions of
synthetic polypeptides (chains of amino acids in a specific
sequence) that are applied to the scalp to stimulate hair
growth over the entire scalp, not just the crown. They are
named for their flexible characteristics when binding to the hair
follicle cells.
How does FLEX S1, 2 work?
Our researchers have found that DHT (dihydrotestosterone)
hormone levels play a key role in the slow development of male
pattern baldness, but there are other negative factors that
"shut down" the hair follicle much faster by binding
to a specific cellular receptor site on the surface of the hair
follicle cells.
Once
these negative factors bind to the specific receptor site and "switch
off" the follicle, hair loss and thinning of the hair
diameter can occur at a frightening rate.
FLEX
S1, 2 work directly on these hair follicle scalp receptors and
"switch on" the hair follicle. This not only
places the follicles back into growth phase but stimulates the
follicle to increase back to a normal diameter and colour.
What about the slick bald areas or temples, does FLEX S1, 2
work there?
We have found FLEX S1, 2 to initiate hair growth in all areas of
the human scalp with equal potency. Furthermore, our
researchers have found that even in slick bald areas of the scalp,
all of the hair follicles remain, though in a miniaturized state.
It now appears that all of the hair may be restored with
continued application.
How well does FLEX S1, 2 work?
Growth in all subjects occurred within 40 days over the entire
scalp. Tiny vellus hairs began to become darkly coloured and
large (terminal) at approximately 90 days of application,
please see the Photo
section.
How long will it take to restore full density of hair?
That
would depend on several factors, though our current theory
estimates it to take between one third (1/3) and one half (1/2) of
the time that a patient was losing their hair to replenish the
scalp to full density. This
may change as research proceeds.
Once available, will I have to use the treatment forever?
Once
hair is restored to a cosmetically acceptable result, it is
anticipated that the patient would have to continue application
to ensure continued hair growth.
These are the questions that we are working hard at in a
research setting now.
How often was FLEX S1, 2 applied?
In the initial study, the FLEX S synthetic peptides were applied
in our SeaGulls delivery vehicle nightly.
Were there any negative side effects noted?
The only negative side effect noted was a contact rash in 5% of
the subjects.
Is FLEX S1, 2 effective in other forms of hair loss?
We are currently testing other Flexible and Folding
peptides in other forms of alopecia, but it is too early to
determine effectiveness at this stage
FLEX
S1, 2 - SAFETY PROFILE
The initial safety
profile of Flex S1,2 has been established. The
synthetic peptide does not inhibit wound healing and is not
catatonic to cultured keratinocyte skin cells. It is not a
dermal irritant, nor does it induce contact sensation.
The
peptide is not a mammalian or bacterial mutagen. Acute and
chronic systemic toxicity studies have established a safe dose,
which is a multiple of the efficacious dose for Flex S1,2.
In
fact, Flex S1 falls under the FDA cosmetic designation according to
the Federal Food, Drug, And Cosmetic Act (FD&C ACT). The
legal staff is evaluating Flex S2 at this time.
The
safety trials for the more potent PEZ peptide have been arranged for
January 2003.
All
WSMR Related Stories:
WSMR
Press Release - Synthetic Peptide
WSMR Frequently Asked Questions + Safety Profile
WSMR Flexible Peptide S patient results
WSMR received seal of approval from JTR
WSMR test patient request form
Dr. Kenneth Skinner of WSMR speaks about HairSwitch
Interim update from WSMR HairSwitch peptide trialist.
HairSite spoke to WSMR's HairSwitch peptide trialists.
March 1, 2003: first official update from HairSwitch peptide
trialists.
November 2003: before and after photos.
Dr. Jankovic's comments about WSMR.
Alert: Please
be advised that HairSite is NOT recommending WSMR products to any of
our readers. Please exercised caution if you are considering
purchasing WSMR products as we are unable to verify if the product
is indeed effective for hair growth or otherwise. Also, while there
is no incriminating evidence which suggests that WSMR is a scam, we
believe that our readers should familiarize themselves with the
latest report by Rock Mountain News about WSMR. Click
here for JTR's post.
TOPICAL
FORUM
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