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The
following was sent to Dr. Gho
Jan 29, 2002 |
Dear
Dr. Gho
Hope
you are well.
It
was almost a year ago since our last meeting and
HairSite's visitors are becoming anxious again as to the
progress of your research.
We
have taken the liberty to compile in HairSite another list of
questions about HM during the past three months. While we have
no intention to impose on you to answer each and every single
question, any new developments that you can share with us would
be greatly appreciated. In particular, BioAmide has
generated a lot of excitement in our forums lately and
many would definitely like to know your views about this company
as well.
I
understand that the attached list of questions is an
overwhelming request by any means. If you prefer, I would be
pleased to meet with you again at your convenience for a quick
update about your research.
Thank you again for your time and I look forward to hearing
from you soon.
Regards,
<edited>
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Availability
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| 1 |
Can you give us a
more precise estimate as to when HM will become available in the
Netherlands and the rest of the world ? How much sooner will
Hair Multiplication become available in the Netherlands than in
other countries ? Will the clinic in the Netherlands be accepting
foreign patients ? |
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Candidates
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| 2 |
How do you determine if a patient is a good candidate for HM ? Will there
be a preliminary test to evaluate if a patient is responsive to the treatment ?
Do you test HM on a small area on the patient to see if it works before
you perform something more extensive ? |
| 3 |
Can HM benefit men
and women with diffuse androgenetic alopecia ? |
| 4 |
Will HM work on
scar tissue from past hair transplant procedures ? |
| 5 |
Would your
treatment work for people who have suffered from hairloss due to
Accutane treatment or Vitamin A overdose? Or, in general, would it
work for people who have suffered from drug induced hairloss (if
drug treatment has
stopped)? |
| 6 |
Will the process of extracting hairs and determining their fitness for HM have an problem
with follicles currently active by Propecia or Minoxidil ? In order words, does someone
taking any kind of hair growth agent make identifying DHT resistant hair follicles more difficult ? |
| 7 |
How long does a
patient have to wait between HM sessions ? |
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Competition
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| 8 |
Are you aware of the current "cell therapy"
experiments being researched by physicians such as Dr. Walter Unger (University of Toronto)? What do you think of his research ? Is Dr. Unger doing
essentially the same thing as you are ? Is there a fundamental difference between your
"Hair Multiplication" and his "cell therapy" or are the differences just a matter of the variety
of cells used ? |
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Cost
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| 9 |
You previously stated that you had no intention of taking
advantage of the situation and making everyone pay an
exorbitant price for the treatment. Exorbitant is a
relative word. Could you give an approximate ceiling to the cost? For a Norwood 7 to regain all his hair, would it cost
him less than $10,000, $20,000, $30,000, etc? |
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Diffuse
Alopecia
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| 10 |
Consider a man who is extensively bald with diffuse androgenic alopecia so that he even has very little DHT resistant hair on his sides and back. Can you give him a full head of hair at a reasonable cost and in a reasonable time. |
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Density
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| 11 |
What kind of
density can we achieve ? Can we have a density like what we used to have when we were teenagers assuming
we can afford numerous HM procedures ? |
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General
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| 12 |
Do you expect the
results of HM to be truly undetectable ? Can people detect that
someone has HM done ? |
| 13 |
How does a doctor
go about licensing HM procedure from you ? |
| 14 |
Have you been able to grow cosmetically acceptable hair on your test subjects ?
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Hair
Cycle
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| 15 |
If the cultured
hair cells exhibit the same properties, will the new hair go
through the hair cycle (anagen, catagen, telogen) all at the same
time ? What are the possibilities that the new hair will fall off
simultaneously if they go through telogen all at the same time
? |
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Hair
Transplant
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| 16 |
If I am
considering getting conventional hair transplants from you today, would you recommend
that I visit your clinic and inquire about hair transplants or should I just wait for your HM
to become available ? Does your clinic still provide conventional hair transplants ? |
| 17 |
Were the results of
your procedure cosmetically as good as a typical hair transplant
in achieving an appearance of fullness of hair (overall appearance of density). |
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ISO
Certification
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| 18 |
Can you tell us
the progress with ISO Certification ? |
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Legal
Issues
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| 19 |
Do you intend to vigorously enforce your 1998 patent ? Are further patents planned
reflecting your most recent work ? Are you aware of the 1996 law passed in the U.S which
prohibits patent infringement lawsuits against doctors who use medical procedures
patented by others after the law became effective ? |
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Last
April's Questions Revisited
Dr. Gho's answers to the following questions last April were
"more info will be forthcoming", so we will ask Dr. Gho
the same questions again this time. |
| 20 |
What kind
of density can be achieved, in hairs/cm2 ? Can a second HM
procedure give a greater density ? |
| 21 |
How long
does it before the new hair follicles start to grow from the time
when we first visit your clinic ? |
| 22 |
What is
the success rate of HM ? Does it work for everyone ? Who would be
the best candidates ? |
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Patients
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| 23 |
Can we see before and after pictures of test subjects from the clinic ? |
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Technical
Questions
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| 24 |
Have you
experimented with germinative epidermal cells (term used by Dr.
Jahoda), and if so, have you discontinued your interest in this
direction?
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| 25 |
Will the new hair grow only where there was once used to be hair or will they
grow wherever the cultured cells are injected regardless of whether there used to
be hair or not on the scalp ? |
| 26 |
How can you
identify proper donor hair if someone just started losing his hair
? |
| 27 |
The permanent hair at the sides and back are somewhat miniaturized in men
who have extensive baldness. Are these miniaturized permanent hair suitable
for culturing and if so, will the new hair inherit the characteristics of these
miniaturized permanent hair and stay thin ? |
| 28 |
Are completely new follicles created or are old ones used with the addition of new HM
cells ? The patent seems to suggest that new follicles are induced to grow, is this accurate ? |
| 29 |
If old follicles are induced to produce terminal hairs, what will prevent the cells in the matrix
from still reacting to DHT or whatever is ultimately responsible for the follicle
miniaturization from continuing to occur, making a treatment only a temporary solution ? |
| 30 |
If old follicles are being rejuvenated in the process, can we rejuvenate all old follicles regardless
of how long they have remained inactive ? |
| 31 |
In HM, are you removing cells from follicles in
non-DHT-affected areas, culturing those cells, and then transplanting or
injecting the resulting cell lines INTO dormant follicles in balding areas of the
scalp to stimulate the cells in those dormant follicles? In other
words, does HM cause follicular neogenesis, ie: does it create brand new hair follicles which
previously did not exist, and is this the PRIMARY mechanism by which HM grows
hair ? |
| 32 |
Since you are injecting via the sweat pores, is the
functionality of the injected sweat pore retained after it is injected, or is it in some way changed
or damaged ? |
| 33 |
If new follicles are being formed, do their structures form and grow in the skin,
or by using the existing balding follicle structure in some way, or form in and grow in the
sweat pores? |
| 34 |
Do the cells injected with a single injection disperse when injected in the scalp and form follicles in
somewhat different areas, or does each injection lead to only a single new follicle site, even if it turns
out to be a multi-lobed follicle or two follicles jammed together etc. |
===================
|
Information about this article |
| Article # |
189 |
| Title |
Copy
Of Letter Faxed To Dr. Gho, Jan 29, 2002 |
| Date |
01/29/02 |
| Source |
HairSite |
| Forum |
Research |
| Archive |
Research |
| Contact |
hairsite@aol.com |
|
Clinically
Proven
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